Lois Patrice Griffin is a main character from the animated television series Family Guy. She is voiced by writer Alex Borstein and first appeared on television, along with the rest of the family, in the 15-minute short on December 20, 1998. Lois was created and designed by series creator Seth MacFarlane. MacFarlane was asked to pitch a pilot to the Fox Broadcasting Company based on Larry and Steve, a short he made which featured a middle-aged character named Larry and an intellectual dog, Steve. After the pilot was given the green light, the Griffin family appeared on the episode "Death Has a Shadow". Lois is the mother of the Griffin family. With her husband Peter, she has had three children: Meg, Chris, and Stewie. Lois is often portrayed as a stereotypical television mother, despite her admitting to being a recovering methamphetamine addict and a kleptomaniac. Lois has also had several affairs, one of which allegedly resulted in the conception of Meg. She has appeared in other media relating to Family Guy—including a video game, commercials and books—and inspired an entire line of merchandise.
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PPeople
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VTV
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FOX | Animated | 1999 - 2025 | Returning Series | 23 Seasons | 487 Episodes Seth MacFarlane, Alex Borstein, Seth Green
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TBS | Animated | 2005 - 2025 | Returning Series | 19 Seasons | 458 Episodes Seth MacFarlane, Wendy Schaal, Rachael MacFarlane
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MTV | Animated | 1991 - 2023 | Ended | 5 Seasons | 56 Episodes John Kricfalusi, Billy West
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MTV | Animated | 1993 - 2023 | Ended | 8 Seasons | 239 Episodes Mike Judge
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FXX | Animated | 2010 - 2023 | Ended | 14 Seasons | 154 Episodes H. Jon Benjamin, Aisha Tyler, Chris Parnell
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FOX | Animated | 2011 - 2025 | Returning Series | 15 Seasons | 369 Episodes H. Jon Benjamin, Dan Mintz, Eugene Mirman
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AMC | Drama | 2007 - 2015 | Ended | 7 Seasons | 95 Episodes Jon Hamm, John Slattery, Vincent Kartheiser
cComics
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Audience Affinity
Animation
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Animation TV
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Sports
57
Hip Hop Music
25
Action & Adventure Movies
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Action & Adventure
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Comedy
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Comedy TV
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About This Data

Scores are based on affinity (correlated voting by visitors to Ranker.com). Positive numbers show the degree of positive affinity for an item by fans of another item; negative numbers show the degree of negative sentiment.